| Commonwealth Care Alliance | Boston, MA | $104M | — | 2023 |
| Burns & Levinson LLP | Boston, MA | $101M | 165 | 2024 |
| Sage Therapeutics, INC. | Cambridge, MA | $96M | 713 | 2025 |
| Harte Hanks, INC. | Chelmsford, MA | $82M | 2,569 | 2024 |
| Casa Systems, INC. | Lowell, MA | $71M | 404 | 2024 |
| Stratus Technologies, INC. | Maynard, MA | $66M | — | 2023 |
| Cambridge College | Boston, MA | $53M | 720 | 2024 |
| Massachusetts Society For The Prevention Of Cruelty To Animals | Boston, MA | $50M | — | 2023 |
| Christmas Tree Shops | Middleborough, MA | $49M | — | 2023 |
| Brockton Radiological Associates, INC. | Brockton, MA | $42M | 16 | 2024 |
| Marklogic Corporation | Burlington, MA | $41M | — | 2023 |
| Edelstein & Company, LLP | Boston, MA | $38M | 208 | 2024 |
| Western Mass Gastroenterology Associates, P.C. | Springfield, MA | $37M | 30 | 2023 |
| Becker College | Foxboro, MA | $36M | 346 | 2024 |
| Gradco, LLC D/b/a Gradient | Cambridge, MA | $35M | 229 | 2024 |
| Sports Medicine North Orthopaedic Surgery, INC. | Peabody, MA | $35M | — | 2023 |
| Jon-don, LLC | Hopedale, MA | $31M | 545 | 2025 |
| Burns & Levinson LLP | Boston, MA | $29M | 189 | 2024 |
| Brockton Hospital, INC. | Brockton, MA | $29M | 494 | 2025 |
| Sullivan Paper Company, INC. | West Springfield, MA | $26M | — | 2024 |
| Forma Therapeutics, INC. | Watertown, MA | $25M | — | 2023 |
| Myorthos Holdings, LLC | Wakefield, MA | $25M | 683 | 2025 |
| Drift.com, INC. | Boston, MA | $24M | 599 | 2024 |
| Metrowest Radiology Associates, INC. | Framingham, MA | $24M | 13 | 2024 |
| Beverly Anesthesia Associates, INC. | Danvers, MA | $23M | 46 | 2024 |
| Intrinsix Corp. | Marlborough, MA | $23M | — | 2021 |
| Spectrum Pharmaceuticals, INC. | Boston, MA | $22M | — | 2023 |
| Eastern Bank | Boston, MA | $21M | 485 | 2025 |
| Cambridge Bancorp | Boston, MA | $21M | 485 | 2025 |
| Eqrx International, INC. | Cambridge, MA | $19M | 387 | 2024 |
| S.g. Torrice CO., INC | Wilmington, MA | $17M | — | 2023 |
| Katz, Nannis & Solomon, P.C. | Waltham, MA | $16M | 110 | 2025 |
| World Education, INC. | Boston, MA | $16M | — | 2023 |
| Hirshberg Dental Associates Of Boston, P.C. | Boston, MA | $15M | 43 | 2025 |
| Cadmus Holding Company, INC. | Waltham, MA | $15M | — | 2023 |
| Sullivan Bille, P.C. | Andover, MA | $15M | 56 | 2025 |
| Walsh Engineering Services, INC. | Chelmsford, MA | $15M | 110 | 2025 |
| Goody, Clancy & Associates, INC. | Boston, MA | $15M | 66 | 2023 |
| Jounce Therapeutics, INC. | Cambridge, MA | $15M | — | 2023 |
| Tsoi/kobus & Associates, INC. | Boston, MA | $15M | 82 | 2025 |
| Akili Interactive Labs, INC. | Boston, MA | $14M | 159 | 2024 |
| International Planning Group, INC. | Wellesley, MA | $13M | 45 | 2024 |
| Rave Wireless, INC. | Framingham, MA | $13M | — | 2023 |
| Anokiwave, INC. | Billerica, MA | $13M | 106 | 2024 |
| Cogito Corporation, INC. | Boston, MA | $13M | 164 | 2024 |
| Morris Holdings LLC | Mansfield, MA | $13M | 180 | 2025 |
| Mccarthy, Mambro, Bertino, LLC | Boston, MA | $13M | 117 | 2024 |
| Power Products Systems, LLC | Wakefield, MA | $12M | — | 2023 |
| Gearscrm, INC. | Needham, MA | $12M | 116 | 2023 |
| Onprocess Technology, INC. | Boston, MA | $12M | 294 | 2024 |
| Apothecary By Design Acquisition CO., LLC | Waltham, MA | $12M | 230 | 2024 |
| Rothtec Engraving Corp | New Bedford, MA | $11M | 36 | 2025 |
| Lown Cardiovascular Group, INC. | Chestnut Hill, MA | $11M | 27 | 2025 |
| S&g, LLP | Worcester, MA | $11M | 53 | 2025 |
| Bradford Labs, LLC | Haverhill, MA | $11M | 17 | 2024 |
| Codiak Biosciences, INC. | Cambridge, MA | $11M | — | 2023 |
| North Suburban Cardiology Associate S, P.C. | Stoneham, MA | $11M | 24 | 2025 |
| Complete Payroll Solutions | Springfield, MA | $10M | — | 2023 |
| Centra Technology, INC. | Burlington, MA | $10M | — | 2023 |
| Reichheld Ting Orthodontics, PC | Westford, MA | $10.0M | 48 | 2024 |
| Ems Engineered Materials Solutions, LLC | Attleboro, MA | $9.9M | 77 | 2024 |
| Albireo, INC. | Cambridge, MA | $9.9M | — | 2023 |
| Alert Innovation INC. | North Billerica, MA | $9.6M | — | 2023 |
| Fletcher Spaght, INC. | Boston, MA | $9.5M | 27 | 2024 |
| First Realty Management Corp. | Boston, MA | $9.5M | 80 | 2023 |
| Patriot Pediatrics, P.C. | Bedford, MA | $9.5M | 28 | 2026 |
| Clough USA, INC. | Foxborough, MA | $9.4M | — | 2024 |
| Diamond Antenna And Microwave Corporation | Littleton, MA | $9.4M | 90 | 2026 |
| M & M Transport Services, INC. | West Bridgewater, MA | $9.3M | — | 2023 |
| Downstream Technologies, LLC | Marlborough, MA | $9.2M | 14 | 2025 |
| Lyndra Therapeutics, INC. | Foxborough, MA | $9.2M | 136 | 2025 |
| Curley & Curley, P.C. | Hingham, MA | $9.0M | 12 | 2023 |
| Homology Medicine, INC. | Waltham, MA | $8.9M | 150 | 2024 |
| Esdaile, Barrett, Jacobs & Mone, LLP | Boston, MA | $8.7M | 18 | 2024 |
| Glidefast Consulting LLC | Woburn, MA | $8.7M | 354 | 2024 |
| Allergy Associates, INC. | North Dartmouth, MA | $8.5M | 26 | 2024 |
| Powers & Sullivan, LLC | Wakefield, MA | $8.5M | 51 | 2024 |
| Eli Group LLC | Cambridge, MA | $8.4M | 5 | 2024 |
| Paresky Flitt & Company , LLP | Wayland, MA | $8.3M | 35 | 2024 |
| North Shore Ambulatory Anesthesia Partners | Peabody, MA | $8.2M | 6 | 2024 |
| Leslie S. Ray Insurance Agency, INC. | Beverly, MA | $8.2M | 24 | 2025 |
| J. M. O'brien & Company, P.C. | Springfield, MA | $8.0M | 18 | 2024 |
| Air Distribution Corporation | Brockton, MA | $7.9M | 48 | 2025 |
| Sunnyside Motor Company, INC. | Holden, MA | $7.7M | 36 | 2025 |
| The Energy Federation, INC. | Marlborough, MA | $7.6M | 124 | 2024 |
| Pinsly Railroad Company, INC. | Westfield, MA | $7.6M | 45 | 2023 |
| J. Frank Conley, INC. | Brockton, MA | $7.5M | 24 | 2025 |
| Bay State Business Products INC | Norwell, MA | $7.5M | 14 | 2024 |
| Knight Oil, INC. | Salisbury, MA | $7.3M | 9 | 2024 |
| Merrimack Urology Associates, P.C. | Chelmsford, MA | $7.2M | 15 | 2023 |
| Pioneer Valley Anesthesia LLC | Brockton, MA | $7.2M | 13 | 2024 |
| Micro-precision Technologies, INC | Rading, MA | $7.2M | 17 | 2025 |
| Green International Affiliates, INC | Tewsbury, MA | $7.2M | 108 | 2025 |
| Rockland Trust | Rockland, MA | $7.1M | 54 | 2025 |
| Artisan Power | Natick, MA | $7.1M | 7 | 2025 |
| Inozyme Pharma, INC. | Boston, MA | $7.1M | 92 | 2025 |
| Parlance Corporation | Woburn, MA | $6.9M | 58 | 2025 |
| Fallon Service, INC. | Quincy, MA | $6.9M | 102 | 2024 |
| Mackie Shea Durning, PC | Boston, MA | $6.7M | 7 | 2023 |
| Brookline Bancorp, INC | Boston, MA | $6.7M | 926 | 2025 |
| Bridge Information Systems, INC. | Boston, MA | $6.7M | 64 | 2025 |
| Hampshire Pathologists, INC. | Brockton, MA | $6.7M | 3 | 2025 |
| Rpg Liquidating, INC. | West Wareham, MA | $6.6M | 43 | 2024 |
| Cooley Shrair, P.C. | Springfield, MA | $6.5M | 3 | 2023 |
| Parker-torres Design INC | Sudbury, MA | $6.4M | 27 | 2024 |
| Plastic Distributors & Fabricators, INC. | Haverhill, MA | $6.4M | 52 | 2025 |
| York Ford, INC. | Saugus, MA | $6.4M | 81 | 2023 |
| Saulino & Silvia, P.C. | Fall River, MA | $6.3M | 6 | 2025 |
| Sigilon Therapeutics, INC. | Cambridge, MA | $6.3M | 124 | 2024 |
| Nauset Marine, INC. | Orleans, MA | $6.3M | 52 | 2024 |
| Capaccio Environmental Engineering, INC. | Marlborough, MA | $6.2M | 39 | 2024 |
| Fred C. Church,inc. | Lowell, MA | $6.2M | — | 2023 |
| Ryan Seamless Gutter Systems, INC. | Westwood, MA | $6.2M | 21 | 2025 |
| Integrated Statistics Incorporated | Woods Hole, MA | $6.1M | 140 | 2024 |
| Tracon Pharmaceuticals, INC. | Foxborough, MA | $6.1M | 25 | 2024 |
| Wilbraham Orthodontics, P.C. | Wilbraham, MA | $6.0M | 2 | 2024 |
| Boston Financial Management LLC | Boston, MA | $6.0M | 59 | 2025 |
| Dyer/brown & Associates, INC. | Boston, MA | $6.0M | 93 | 2025 |
| Frank P. Fechner, MD, LLC | Worcester, MA | $6.0M | 23 | 2024 |
| Robert C. Cantu, M.D. Neurological Surgery, INC. | Concord, MA | $5.9M | 3 | 2024 |
| The Montgomery Company, Incorporated | Sturbridge, MA | $5.9M | 17 | 2025 |
| Cardiology Internists Of Leominster, INC. | Leominster, MA | $5.8M | 30 | 2023 |
| Gustavo Preston Company, INC. | Chelmsford, MA | $5.8M | 90 | 2023 |
| Eo Vista | Acton, MA | $5.8M | 35 | 2023 |
| Mama Rosie's Company, INC. | Charlestown, MA | $5.8M | — | 2023 |
| Strem Chemicals INC. | Newburyport, MA | $5.7M | — | 2023 |
| Grassi Associates, INC. | Framingham, MA | $5.7M | 6 | 2024 |
| Subaru Of Wakefield, INC, | Wakefield, MA | $5.7M | 77 | 2025 |
| Numerated Growth Technologies, I | Boston, MA | $5.7M | 107 | 2025 |
| Allied Machined Products Corp. | Auburn, MA | $5.7M | 49 | 2024 |
| Greater Newburyport Emergency Physicians, INC. | Bedford, MA | $5.7M | 20 | 2025 |
| Pharmalex US Corp | Burlington, MA | $5.7M | 98 | 2023 |
| Crosby, Schlessinger & Smallridge, | Boston, MA | $5.6M | 15 | 2024 |
| Finch Therapeutics Group, INC. | Boston, MA | $5.5M | 104 | 2025 |
| Sturbridge Professional Services, P.C. | Southbridge, MA | $5.5M | 11 | 2024 |
| Kellys Roast Beef, INC. | Saugus, MA | $5.5M | 113 | 2025 |
| Benoit & Mcardle, P.C. | Marion, MA | $5.5M | 13 | 2025 |
| Metropolitan Air Conditioning/heating, INC. | Everett, MA | $5.5M | 11 | 2025 |
| Groton Medical Associates, LLC | Groton, MA | $5.5M | 26 | 2023 |
| Coastal Engineering CO INC | Orleans, MA | $5.4M | 56 | 2024 |
| Sqz Biotechnologies Company | Watertown, MA | $5.3M | 136 | 2024 |
| Endo INC Root Canal Specialists North Shore | Salem, MA | $5.2M | 24 | 2025 |
| Allergy & Asthma Treatment Specialists, P.C. | Framingham, MA | $5.2M | 11 | 2024 |
| Behavioral Development & Educational Services, LLC | Holliston, MA | $5.2M | 56 | 2025 |
| Applied Management Systems, INC. | Burlington, MA | $5.1M | 15 | 2024 |
| New England Orthopedic Specialists, LLC | Peabody, MA | $5.1M | 43 | 2023 |
| Barrett A Hurwitz | North Dartmouth, MA | $5.1M | 1 | 2023 |
| Elder Services Of Cape Cod And The Islands, INC. | South Dennis, MA | $5.1M | — | 2023 |
| Sterling Concrete, Corp. | North Oxford, MA | $5.0M | 59 | 2024 |